Zabbix_server do not start (even after rebooting the machine)

Correct. You need a custom template for persistance.

Create custom template dir:

mkdir -p /etc/e-smith/templates-custom/etc/zabbix/zabbix_server.conf

Create /etc/e-smith/templates-custom/etc/zabbix/zabbix_server.conf/90custom with following content:

# 90custom - additional settings
CacheSize=128M

Apply config:

signal-event nethserver-zabbix-update

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