Is there a possibility to do a nested folder structure with Shares Folders? For example I would like to have /1000/test/ and I would like to have Person A and Person B to have read/write permissions in /1000, but only Person A should have read/write permissions in /1000/test.
I could create Folders in the root folder with a user with write permissions, but then all the permissions are inherited from the root folder for all users I guess.
Thanks!
Linux is not MS 
It’s possibile. You need a windows client to assign permissions.
Give permissions of FS level. I do have an MS background and back then I never gave permissions based on shares, only on FS level (ntfs in MS environments)
Do you mean through Right-Click on the folder → Properties → Security? Also from what I understand I can assign permissions from one windows client for all users right? The aim is to have a folder which I can just add for everyone as a net drive and in this folder there are subfolders with different permissions for the users. Note that the clients are not in a domain.
Exactly. 
The clients should be able to respect Windows ACL.
Wouldn’t it be actually possible to give permissions for folders or documents through chmod/chown directly on the terminal on nethserver?
no
Yes, it’s possible to use the terminal. The command is setfacl, but it’s usage it’s not simple.