RAID-1 for full system - GPT - UEFI

RedHat’s irrational aversion to ZFS is a real shame–Proxmox can do exactly what you want, with ZFS goodness on top, but of course it’s Debian-based, not EL-based. It is possible to hack CentOS/Neth to boot from a ZFS mirror, but not really something I’d recommend for production use: