How to vote? I guess you must to sign up first, no?
You already know my opinion about NS as “All In One” product.
Because of that, I’m totally agree with “alientity” regarding to separation of the services (but not with pfSense!) and with “FrostMute” (I hope he was refered to NS in reply to “alientity”!).
Again, my opinion regarding how to use NS, mostly for Business Environment:
one appliance directly connected to WAN as UTM: Firewall, Web Proxy and Filter, Mail Proxy and Filter (SMTP, POP3, AV, Antispam), F2B, VPN, IPS, …
one appliance connected to GREEN as PDC/AD (File Server, Monitoring and Inventorying, Print server, …).
at least one appliance connected to ORANGE for: Web hosting, Mail hosting, ownCloud, FTP, …
And, of course, settings from WebUI, as much is possible!